Thank you so much for reporting on this - I hadn’t heard of the most recent study with mice. Animals can contract Covid and develop Long Covid, too. I’m relieved to have validation of this, because it’s a conversation I have repeatedly with people, but usually only the ones closest to me because no one takes that kind of conversation seriously. It’s hard to get the general population to acknowledge Long Covid in people, let alone animals.
I know I’ve commented before on how much your newsletter means to me, but it really, really does. I worry the majority of the medical community has forgotten about us. It’s a relief when I get your newsletter in my inbox and know there are doctors who care and continue to follow the research.
Thank you! (I read the report from den Dunnen’s lab earlier today; it’s fascinating. In the introduction the authors cited another study (Achleiter et al in Mol Psychiatry. 2023; 28(7): 2872-2877) re use of therapeutic apheresis for folks with LC (assoc’d with reduction in autoantibodies, among other things). It’s interesting that folks are developing autoimmune disorders post-Covid and that people with preexisting autoimmune disorders are more likely to develop LC (E. Jacob’s et al in J of Autoimmunity. 2023; 135: 102991). So much to wonder about!
Thanks for the info Laura. Apheresis does help some, but it is an invasive procedure with risks especially in a population that can clot more easily. The den Dunnen article is very interesting since they gave the mice total IgG from the LC patients. There may be autoantibodies for which we do not yet have tests.
Yes! That’s part of my wondering. And what are the triggers? And is there a safety catch to put on? That the LC pts IlG had an effect on the mice is so thrilling, especially as too often folks are being told there’s nothing wrong when actually it’s only that the test used were unable to detect what’s
wrong. If only we could fast-forward research! (Thank you for comment re appropriateness of apheresis. )
Thank you so much for reporting on this - I hadn’t heard of the most recent study with mice. Animals can contract Covid and develop Long Covid, too. I’m relieved to have validation of this, because it’s a conversation I have repeatedly with people, but usually only the ones closest to me because no one takes that kind of conversation seriously. It’s hard to get the general population to acknowledge Long Covid in people, let alone animals.
I know I’ve commented before on how much your newsletter means to me, but it really, really does. I worry the majority of the medical community has forgotten about us. It’s a relief when I get your newsletter in my inbox and know there are doctors who care and continue to follow the research.
Thanks Reda
Thank you! (I read the report from den Dunnen’s lab earlier today; it’s fascinating. In the introduction the authors cited another study (Achleiter et al in Mol Psychiatry. 2023; 28(7): 2872-2877) re use of therapeutic apheresis for folks with LC (assoc’d with reduction in autoantibodies, among other things). It’s interesting that folks are developing autoimmune disorders post-Covid and that people with preexisting autoimmune disorders are more likely to develop LC (E. Jacob’s et al in J of Autoimmunity. 2023; 135: 102991). So much to wonder about!
Thanks for the info Laura. Apheresis does help some, but it is an invasive procedure with risks especially in a population that can clot more easily. The den Dunnen article is very interesting since they gave the mice total IgG from the LC patients. There may be autoantibodies for which we do not yet have tests.
Yes! That’s part of my wondering. And what are the triggers? And is there a safety catch to put on? That the LC pts IlG had an effect on the mice is so thrilling, especially as too often folks are being told there’s nothing wrong when actually it’s only that the test used were unable to detect what’s
wrong. If only we could fast-forward research! (Thank you for comment re appropriateness of apheresis. )