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Great presentation as usual thank you,

Regarding the new metformin study - I think it relied on a review of patient charts and diagnosis codes of long covid. I’ll have to confirm that, but any study relying on clinical documentation of “long covid” will vastly underestimate the true prevalence. It’s hard to make that diagnosis as it is somewhat of a judgment call, and there are no consensus confirmatory tests like blood work ( although there are lots of suggestive tests). I like the studies that prospectively assess long covid symptom development via surveys, etc rather than mining icd 10 codes. What do you think? I trust the Covid-OUT ~40% RR reduction more, though I would have to review how they measured this, but it was prospective.

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Wow. A lot of information there, thank you.

Some eye openers too. Like 50% of US think they will never get Covid again in their lifetimes 😬

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